Tuesday, May 13, 2008

Pedigree Analysis, Albinism


Albino is one of the disease affected by autosomal recessive.
There are several kinds of modes of heritance such as Autosomal dominant and recessive, X-linked dominant and recessive. Each modes of heritance has different traits and some disease occur because of the traits.

Albino is one of example for Autosomal recessive and tt is quite famous in the world. There are several kinds of disease in albino but main character of these diseases is luck of pigmentation of the skin and the hair either completely or partially. Dr Bossy found that mutations in genes that regulate the multi step process of melanin synthesis, distribution of pigment by the melanocyte, and/or melanosome biogenesis are the basis for these diseases. It is hard to live for animal with albino because of white colour being found out from predators easily. For human beings, because of luck of pigmentation of the skin, the rate of skin cancer is really high. People with albino must use sun cream but it is not possible to avoid sunburn with only using sun cream in some region such as Africa.

Like albino, there are lots of disease affected by atosomal dominant and recessive and X-linked dominant and recessive.

The souce is from http://www.emedicine.com/derm/topic12.htm

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